Drug Detox Drug Detox Bookmark  |   Send to a Friend (anonymously)  |   Privacy Policy  |   Site Map

LUVOX CR

LUVOX CR
Luvox Cr

DESCRIPTION / DEFINITIONS: Luvox Cr® (fluvoxamine maleate) is a selective serotonin reuptake inhibitor.

ABUSE: Luvox Cr is a drug prescribed for the treatment of depression.

ADDICTION / DEPENDENCE: Half life and metabolism, Black Box Warning.

SIDE EFFECTS: Heart attack, suicide, paranoid reactions (see list below).

WITHDRAWAL SYMPTOMS: Nausea, insomnia, electric shock like sensations (see list below).

TREATMENT: Medical detoxification.

DESCRIPTION / DEFINITIONS

Luvox Cr® (fluvoxamine maleate) is a selective serotonin reuptake inhibitor (“SSRI”). Although there are no medical tests to determine if a person has insufficient serotonin, SSRI drugs like Luvox Cr increase the amount of serotonin in the brain. According to its label, “The mechanism of action of fluvoxamine maleate in obsessive compulsive disorder is presumed to be linked to its specific serotonin reuptake inhibition in brain neurons.”

ABUSE

Abilify is a drug prescribed for the treatment of depression.

ADDICTION / DEPENDENCE

HALF LIFE AND METABOLISM

The biological half life of a substance is the time it takes for a drug to lose half of its pharmacologic activity. This is significant because it affects how soon withdrawal symptoms may appear.

The half life of Luvox Cr is 16 hours.

Luvox Cr is mainly metabolized through the P450 pathway in the liver and the enzymes primarily handling the metabolism is CYP3A4.

The CYP enzymes are the major enzymes involved in drug metabolism, and since many drugs may increase or decrease the activity of various CYP isozymes, this is a major source of adverse drug interactions, since changes in CYP enzyme activity may affect the metabolism and clearance of various drugs. For example, if one drug inhibits the CYP-mediated metabolism of another drug, the second drug may accumulate within the body to toxic levels, possibly causing an overdose.

BLACK BOX WARNING

The Food and Drug Administration (FDA) has decided that some drugs pose very serious risks and have required these drugs have what is called a black box warning. Luvox Cr has a black box warning. Here is the warning.

WARNING: Suicidality and Antidepressant Drugs

Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of major depressive disorder (MDD) and other psychiatric disorders. Anyone considering the use of Luvox Cr or any other antidepressant in a child, adolescent, or young adult must balance this risk with the clinical need. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24; there was a reduction in risk with antidepressants compared to placebo in adults aged 65 and older. Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior. Families and caregivers should be advised of the need for close observation and communication with the prescriber. Luvox Cr is not approved for use in pediatric patients.

(See WARNINGS: Clinical Worsening and Suicide Risk, PRECAUTIONS: Information for Patients, and PRECAUTIONS: Pediatric Use.)

SIDE EFFECTS

The following information is taken from the Luvox Cr label:

  • abdominal pain

  • abnormal dreams

  • abnormal ejaculation

  • abnormal thinking

  • accidental injury

  • accommodation abnormal

  • acne

  • agitation

  • agoraphobia

  • akathisia

  • akinesia

  • allergic reaction

  • alopecia

  • amblyopia

  • amnesia

  • anemia

  • angina pectoris

  • anorexia

  • anorgasmia

  • anuria

  • anxiety

  • apathy

  • apnea

  • arthralgia

  • arthritis

  • arthrosis

  • asthenia

  • asthma

  • ataxia

  • AV block

  • back pain

  • biliary pain

  • body aches/pains

  • bradycardia

  • breast pain

  • bronchitis

  • bursitis

  • cardiomyopathy

  • cardiovascular disease,

  • cerebrovascular accident

  • chest pain

  • cholecystitis

  • cholelithiasis

  • CNS depression

  • cold extremities

  • colitis

  • coma

  • conduction delay

  • congestion of upper airway

  • conjunctivitis

  • constipation

  • convulsion

  • corneal ulcer

  • coronary artery disease

  • cyst

  • cystitis

  • deafness

  • decreased appetite

  • decreased libido

  • dehydration

  • delayed menstruation

  • delirium

  • delusion

  • dental pain

  • depersonalization

  • depression

  • diabetes mellitus

  • diarrhea

  • diplopia

  • dizziness

  • drug dependence

  • dry eyes

  • dry mouth

  • dry skin

  • dyskinesia

  • dysmenorrhea

  • dyspepsia

  • dyspnea

  • dystonia

  • dysuria

  • ear pain

  • ecchymosis

  • eczema

  • edema
  • elevated liver transaminases

  • embolus

  • emotional lability

  • epistaxis

  • eructation

  • esophagitis

  • euphoria

  • exfoliative dermatitis

  • extrapyramidal syndrome

  • eye pain

  • fecal incontinence

  • female lactation

  • fever

  • fibrillations

  • flatulence

  • flu syndrome

  • furunculosis

  • gait unsteady

  • gastritis

  • gastroenteritis

  • gastrointestinal hemorrhage

  • gastrointestinal ulcer

  • generalized muscle spasm

  • gingivitis

  • glossitis

  • goiter

  • hallucinations

  • headache

  • heart failure

  • hematemesis

  • hematospermia

  • hematuria

  • hemiplegia

  • hemoptysis

  • hemorrhoids

  • hiccups

  • hoarseness

  • hostility

  • hypercholesterolemia

  • hyperglycemia

  • hyperkinesia

  • hyperlipidemia

  • hypersomnia

  • hypertension

  • hypertonia

  • hyperventilation

  • hypochondriasis

  • hypoglycemia

  • hypokalemia

  • hypokinesia

  • hypotension

  • hypothyroidism

  • hypotonia

  • hysteria

  • impotence

  • incoordination

  • increase the risk of bleeding events

  • increased appetite

  • increased cough

  • increased libido

  • increased salivation

  • infection

  • insomnia

  • intestinal obstruction

  • jaundice

  • kidney calculus

  • lactate dehydrogenase increased

  • laryngismus

  • laryngitis

  • leukocytosis

  • leukopenia

  • liver function test abnormal

  • loss of appetite

  • lymphadenopathy

  • malaise

  • manic reaction

  • melena

  • menopause

  • menorrhagia

  • metrorrhagia

  • mutism

  • myalgia

  • myasthenia

  • mydriasis
  • myocardial infarction

  • myoclonus

  • myopathy

  • nausea

  • neck pain

  • neck rigidity

  • nervousness

  • neuralgia

  • neurosis

  • nocturia

  • obsessions

  • obstructive pulmonary disease

  • oliguria

  • otitis media

  • overdose

  • pallor

  • palpitation

  • paralysis

  • paranoid reaction

  • paresthesia

  • parosmia

  • pathological fracture

  • pelvic pain

  • pericarditis

  • pharyngitis

  • phlebitis

  • phobia

  • photophobia

  • photosensitivity reaction

  • pneumonia

  • polyuria

  • premenstrual syndrome

  • psychosis

  • psychotic reaction

  • pulmonary infarction

  • pulse irregular

  • purpura

  • rash

  • rectal hemorrhage

  • reflexes decreased

  • retinal detachment

  • rhinitis

  • seborrhea

  • sexual function abnormal

  • sinusitis

  • skin discoloration

  • sleep disorder

  • slurred speech

  • somnolence

  • ST segment changes

  • stomatitis

  • stupor

  • sudden death

  • suicide attempt

  • supraventricular extrasystoles

  • sweating

  • syncope

  • tardive dyskinesia

  • taste loss

  • taste perversion

  • tendinous contracture

  • tenosynovitis

  • thrombocytopenia

  • tooth disorder

  • torticollis

  • tremor

  • trismus

  • twitching

  • urinary incontinence

  • urinary tract infection

  • urinary urgency

  • urination impaired

  • urticaria

  • vaginal hemorrhage

  • vaginitis

  • vasodilatation

  • vertigo

  • viral infection

  • visual field defect

  • vomiting

  • weight gain

  • weight loss

  • withdrawal syndrome

  • yawning

WITHDRAWAL SYMPTOMS

Luvox Cr can be a very difficult drug to stop taking. Here are some of the Luvox Cr withdrawal symptoms:

  • agitation

  • confusion

  • depression

  • diarrhea

  • dizziness

  • dreams, including vivid dreams

  • drowsiness

  • electric shock-like sensations
  • fatigue/malaise

  • feelings of being hot or cold

  • feelings of unreality

  • flatulence

  • flu-like feelings

  • headache

  • insomnia
  • irritability

  • mood wwings

  • muscle spasms

  • nausea

  • other strange tingling or painful sensations

  • sweating

  • tremor

TREATMENT

Withdrawal from Luvox Cr should only be done under the care of a health practitioner. The safest way is to withdraw at an inpatient medical detox facility with a protocol that includes hydration, vitamins and supplements for biological balancing. Call us to talk to a Detox Advisor.
© 2017. All rights reserved. Site designed by
Rigney Graphics